Sterile Processing Exam Prep
CRCST Exam Prep 2026
VoltExam's Sterile Prep is an iOS app for the HSPA CRCST sterile processing technician certification exam — it includes 1,000+ CRCST practice questions across all 6 exam domains and a built-in sterilization parameter reference, for $17.99 with lifetime access, no subscription, works offline.
The CRCST exam covers 6 domains: Cleaning and Decontamination, Preparation and Packaging, Sterilization, Storage and Distribution, Quality Assurance, and Administration. Below you'll find a complete breakdown of each domain with the exact facts that appear on the exam.
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CRCST practice questions
6 of 6
Exam domains covered
~70%
Typical passing score
CRCST Exam Domain Breakdown
The CRCST exam has 150 questions across 6 domains. Here's what each domain tests and what you need to know to pass.
Cleaning and Decontamination
~20%The largest domain on the CRCST exam. Covers PPE requirements for the decontamination area, point-of-use pre-treatment, manual cleaning techniques, ultrasonic cleaners, washer-disinfectors, and disinfection levels (low, intermediate, high). Key facts: SPD technicians must wear full PPE including eye protection, face mask, liquid-resistant gown, and heavy-duty puncture-resistant gloves in the decontamination area. Water temperature for manual cleaning should not exceed 100°F (38°C) — hot water sets protein soils. Enzymatic detergents must be diluted per manufacturer IFU.
Preparation and Packaging
~18%Covers tray assembly, instrument inspection, packaging materials, and labeling requirements. Woven textile wraps must be laundered and inspected for holes before every use. Non-woven (SMS) wraps are single-use. Peel pouches must be heat-sealed — no staples, paper clips, or tape. Rigid sterilization containers must have validated filter retention systems and intact locks. All packages must be labeled with date, sterilizer number, load number, and expiration date. Items in packaging must have space for steam/agent penetration.
Sterilization
~22%Covers all sterilization modalities and their parameters. Steam (autoclave) is the method of choice for heat-stable items. EO is used for heat- and moisture-sensitive items but requires mandatory 8–12 hour aeration to off-gas toxic residuals. Hydrogen peroxide plasma (STERRAD) is fast (~55 min) but incompatible with liquids, cellulose (paper), and long narrow lumens. Low-temperature steam with formaldehyde (LTSF) is used in some facilities. Flash sterilization (IUSS — Immediate Use Sterilization) is only for emergencies when there is insufficient time for standard processing.
Storage and Distribution
~15%Covers sterile storage conditions, shelf life, event-related sterility, case cart systems, and loaner instrument management. Sterile items should be stored in a clean, dry area away from sinks and floor traffic. Temperature should be 64–75°F (18–24°C) with 30–60% relative humidity. Event-related sterility means a package remains sterile unless an event compromises it (damage, moisture, opening). Sterile items should not be stored on the floor or near exterior walls.
Quality Assurance
~15%Covers biological indicators (BIs), chemical indicators (CIs), Bowie-Dick test, and documentation. BIs contain spores — Geobacillus stearothermophilus for steam and H2O2 plasma, Bacillus atrophaeus for EO. BIs must run with every EO load, every implant load (implant quarantined until BI confirms negative), and at minimum weekly for steam. A failed BI requires immediate notification of infection control and recall of all affected loads. Bowie-Dick tests verify adequate air removal in pre-vacuum steam sterilizers and must run daily before the first load.
Administration
~10%Covers inventory management, OSHA bloodborne pathogen standards, staff competencies, documentation, and regulatory compliance. SPD must comply with OSHA 29 CFR 1910.1030 (Bloodborne Pathogens Standard), requiring exposure control plans, hepatitis B vaccination availability, and post-exposure follow-up. Documentation requirements include sterilization load records, maintenance logs, and competency records for all staff. This domain is the smallest on the exam but tests regulatory knowledge that crosses into other domains.
Domain weights are approximate based on HSPA's published exam blueprint. VoltExam's question bank covers all 6 domains.
Sterilization Parameters You Must Memorize
These parameters appear directly on the CRCST exam. Know them exactly — not approximately.
| Method | Temperature | Pressure / Cycle | Notes |
|---|---|---|---|
| Steam — Gravity | 250°F / 121°C | 15 psi / 30 min | Unwrapped instruments (IUSS): 3 min |
| Steam — Pre-vacuum | 270°F / 132°C | 27 psi / 4 min | Bowie-Dick test required daily |
| Ethylene Oxide (EO) | 37–55°C | 2–6 hr exposure | 8–12 hr aeration mandatory; BI = B. atrophaeus |
| H₂O₂ Plasma (STERRAD) | ~50°C | ~55 min | No cellulose/liquids; BI = G. stearothermophilus |
| Flash / IUSS (Gravity) | 270°F / 132°C | 3 min unwrapped | Emergency use only; no implants |
CRCST Exam — Frequently Asked Questions
What is the CRCST exam?
The CRCST (Certified Registered Central Service Technician) exam is administered by HSPA (Health Sterile Processing Association). It certifies sterile processing department (SPD) technicians who decontaminate, sterilize, and distribute surgical instruments in hospitals and surgical centers. The exam has 150 questions and requires a passing score of approximately 70%.
How many questions are on the CRCST exam?
The CRCST exam contains 150 multiple-choice questions covering 6 content domains: Cleaning and Decontamination, Preparation and Packaging, Sterilization, Storage and Distribution, Quality Assurance, and Administration. Candidates need approximately 105 correct answers (70%) to pass.
What are the eligibility requirements for the CRCST exam?
HSPA requires candidates to complete 400 hours of hands-on central service work experience before taking the CRCST exam. Many employers hire candidates before certification and require them to pass within 6–18 months. There is no formal education prerequisite — a high school diploma or GED is sufficient.
What sterilization parameters are on the CRCST exam?
The CRCST exam tests exact sterilization parameters: Steam gravity displacement (250°F/121°C, 15 psi, 30 minutes), Steam pre-vacuum/dynamic (270°F/132°C, 27 psi, 4 minutes), Flash/IUSS gravity (270°F/132°C, 3 minutes unwrapped). Ethylene oxide (EO): 37–55°C, 2–6 hour cycle, 8–12 hour aeration. Hydrogen peroxide plasma (STERRAD): ~50°C, 55 minutes, incompatible with liquids and cellulose.
How long does it take to study for the CRCST exam?
Most candidates spend 8–10 weeks studying for the CRCST exam while working in a central service department. Study sessions of 30–45 minutes daily are more effective than weekend cramming. Focus the first half on decontamination and sterilization parameters (the largest exam domains), then shift to packaging, storage, quality assurance, and administration.
Study Guide
How to Pass the HSPA CRCST Exam in 2026
8–10 week study plan, domain priorities, sterilization parameters to memorize, and biological indicator requirements.
Read the full guide →Ready to Pass Your CRCST Exam?
1,000+ CRCST questions, sterilization parameter reference, and all 6 exam domains covered.